N n-dimethylaniline monooxygenase activity
WebJan 14, 2013 · 1.14.13.8. H (+) + N,N-dimethylaniline + NADPH + O2 <=> H2O + N,N-dimethylaniline N-oxide + NADP (+) A broad spectrum monooxygenase that accepts substrates as diverse as hydrazines, phosphines, boron-containing compounds, sulfides, selenides, iodide, as well as primary, secondary and tertiary amines. Is distinct from other … WebN,N-Dimethylaniline (DMA) Intermediates. ding 2024-04-13T17:29:06+08:00. N,N-Dimethylaniline is an organic compound. It is a colorless to light yellow oily liquid with a pungent odor at room temperature and pressure.
N n-dimethylaniline monooxygenase activity
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WebThe flavin-containing monooxygenases are NADPH-dependent enzymes that catalyze the oxidation of many drugs and xenobiotics. In most mammals, there is a flavin-containing monooxygenase that catalyzes the N-oxidation of some primary alkylamines through an N-hydroxylamine intermediate. http://www.informatics.jax.org/vocab/gene_ontology/GO:0004499
WebAbstract Human liver microsomal flavin-containing monooxygenase activity has been studied using dimethylaniline N-oxidation and thiobenzamide S-oxidation. Except for one subject, the capacity of human liver microsomes to mediate these reactions were markedly increased at pH 8.4 compared to pH 7.4. WebDimethylaniline [N,N-Dimethylaniline], N,N-Dimethylbenzeneamine, N,N-Dimethylphenylamine [Note: Also known as Dimethylaniline which is a correct synonym …
WebDec 8, 2024 · Gene ID: 856581, updated on 8-Dec-2024 Summary Enables N,N-dimethylaniline monooxygenase activity. Involved in protein folding. Located in endoplasmic reticulum membrane. Human ortholog (s) of this gene implicated in hypertension; inherited metabolic disorder; and trimethylaminuria. WebPredicted to enable N,N-dimethylaniline monooxygenase activity and aldehyde oxidase activity. Involved in regulation of cholesterol metabolic process. Predicted to be located in cytosol and endoplasmic reticulum. Is expressed in bladder. Orthologous to human FMO5 (flavin containing dimethylaniline monoxygenase 5). [provided by Alliance of Genome …
WebAbstract Human liver microsomal flavin-containing monooxygenase activity has been studied using dimethylaniline N-oxidation and thiobenzamide S-oxidation. Except for one …
WebN,N-dimethylaniline monooxygenase; localizes to ER membrane and cytosol View computational annotations Molecular Function Manually Curated enables N,N-dimethylaniline monooxygenase activity ( IDA ) Biological Process Manually Curated involved in protein folding ( IDA ) Cellular Component Manually Curated limiting family size pro and consWebJan 14, 2013 · NX_Q99518 - FMO2 - Dimethylaniline monooxygenase [N-oxide-forming] 2 - Function. Catalyzes the N-oxidation of certain primary alkylamines to their oximes via an N-hydroxylamine intermediate. Inactive toward certain tertiary amines, such as imipramine or chloropromazine. Can catalyze the S-oxidation of methimazole. limiting firefox processesWebAcute inhalation exposure to N,N-dimethylaniline has resulted in effects on the CNS and circulatory system, with headache, cyanosis, dizziness, labored breathing, paralysis, and … hotels near swanzey new hampshireWebMetalloporphyrin catalyzed oxidation of methyl yellow and related azo compounds limiting financial liability texasWebN -oxide and S -oxide formation represent the major FMO-mediated reactions In contrast to most CYP isoenzymes, the FMOs bind and activate molecular oxygen before the substrate … limiting food definitionWebN,N-dimethylaniline monooxygenase activity trimethylamine monooxygenase activity Process metabolic process oxidation reduction Cellular Location Endoplasmic reticulum membrane Microsome membrane Gene Properties Chromosome Location 1 Locus 1q24.3 SNPs FMO3 Gene Sequence >1599 bp … hotels near swartz bay terminalWebJan 23, 2007 · TMA is generated by the action of gut microbiota using dietary precursors such as choline, choline containing compounds, betaine or L-carnitine. By regulating … limiting focus/ depth of field